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Beilstein J. Org. Chem. 2013, 9, 1501–1507, doi:10.3762/bjoc.9.171
Graphical Abstract
Figure 1: Assay pipeline for triaging hits. Individual assay cut-offs are given in italics.
Figure 2: Hit compounds selected for further optimization.
Scheme 1: Preparation of substituted methyl 2-(1H-indazol-1-yl)acetates. Reagents and conditions: (a) Et3N, B...